Protocol: Alliance – A222004
Please Note: Below is partial eligibility, for full eligibility requirements, please contact GHCI Research Department at (810)762-8181, (810)762-8079 and/or (810)762-8038. Thank you!
Eligibility:
- Diagnosis of advanced cancer.
- Patient report 2 month weight loss of at least 5 pounds (2.3 kilograms) and/or physician estimated caloric intake of less than 20 calories/kilogram of body weight per day.
- The patient must perceive loss of appetite and/or weight as a problem, and have an appetite score of 4 or worse on the “Please rate your specific appetite” question that requires a patient response on a 0-10 numeric rating scale.
- Not receiving ongoing tube feedings or parenteral nutrition at the time of registration.
- Not currently using systemic adrenal steroids (with the exception of short term dexamethasone within 3 days of chemotherapy for control of chemotherapy side effects).
- No use of androgens, progesterone analogs, or other appetite stimulants withint he past month.
- No Covid-19 infection in the past hat, in the opinion of the treating physician, had left patients with compromised taste, which has not resolved at the time of registration.
- At least 18 years of age.
- Estimated life expectancy of 3 months or longer.
- No treatment with another antipsychotic agent, such as risperidone, quetiapine, clozapine, butyrophenone within 30 days of enrollment.