Treatment of Refractory Nausea

April 8, 2020

PROTOCOL: URCC-16070

SCHEMA URCC 16070

Please Note: Below partial eligibility, for full eligibility requirements, please contact GHCI Research Department at (810)762-8181, (810)762-8079 and/or (810)762-8038. Thank you!

ELIGIBILITY:

  1. Patients must have a diagnosis of breast cancer and be chemotherapy naive. Note: Prior methotrexate for non-cancerous conditions is allowed.
  2. Be scheduled to receive a single day chemotherapy regimen that contains doxorubicin, and/or cyclophosphamide, and/or carboplatin. Herceptin (trastuzumab) and other chemotherapy agents will be allowed with any of these regimens.
  3. Be scheduled to receive an antiemetic regimen that does not contain Akynzeo.  For chemotherapy regimens with a high emetic risk, the antiemetic regimen must include an NK-1 antagonist receptor, a 5HT3 receptor antagonist and dexamethasone. Other antiemetics, including additional dexamethasone and olanzapine, ma also be included at cycle one.  For chemotherapy regimens with a moderate emetic risk, the antiemetic regimen must include a 5HT3 receptro antagonist and dexamethasone. Other antiemetics, including additional dexamethasone and olanzapine, may also be included at cycle one.
  4. Must be at least 18 years of age.
  5. ECOG Performance Status 0-2.

 

Genesys Hurley Cancer Institute

302 Kensington Avenue (Print a Map)
Flint, MI 48503

810-762-8226 | 888-762-8675

Ascension Genesys Hospital
Hurley Medical Center
Michigan Cancer Consortium

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